Publications

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Sneha Mitra, Rohan Malik, Wilfred Wong, Afsana Rahman, Alexander J. Hartemink, Yuri Pritykin, Kushal K. Dey, Christina S. Leslie (2024). Single-cell multi-ome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis. Nature Genetics.

PDF DOI bioRxiv

David Yao, Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R. Doughty, Idan Gabdank, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D. White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J. Greenleaf, Pardis C. Sabeti, Christina Leslie, Yuri Pritykin, Jill E. Moore, Michael A. Beer, Charles A. Gersbach, Timothy E. Reddy, Yin Shen, Jesse M. Engreitz, Michael C. Bassik, Steven K. Reilly (2024). Multicenter integrated analysis of noncoding CRISPRi screens. Nature Methods.

PDF DOI bioRxiv

Sandra Nakandakari-Higa, Sarah Walker, Maria C. C. Canesso, Verena van der Heide, Aleksey Chudnovskiy, Johanne T Jacobsen, Roham Parsa, Jana Bilanovic, S. Martina Parigi, Karol Fiedorczuk, Elaine Fuchs, Angelina M Bilate, Giulia Pasqual, Daniel Mucida, Alice O. Kamphorst, Yuri Pritykin, Gabriel D Victora (2024). Universal recording of immune cell interactions in vivo. Nature.

PDF DOI rdcu bioRxiv

Christopher Alvarez-Breckenridge, Kristin G. Anderson, Ana Luisa Correia, Shadmehr Demehri, Huy Q. Dinh, Karen Olivia Dixon, Gavin P. Dunn, Laura Evgin, Jeremy Goc, Zinaida Good, Nir Hacohen, Patrick Han, Pavel Hanč, John Hickey, Kelly Kersten, Beiyun C. Liu, Aitziber Buque, Yuxuan ‘Phoenix’ Miao, J. Justin Milner, Yuri Pritykin, Ferdinando Pucci, Nicole E. Scharping, Lisa Sudmeier, Yufei Wang, Andreas Wieland, Michelle M. Williams (2023). Lessons for the next generation of scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium. Cancer Immunology Research.

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Gabriel Dolsten, Yuri Pritykin (2023). Genomic analysis of Foxp3 function in regulatory T cells. Journal of Immunology.

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Joris van der Veeken, Clarissa Campbell, Yuri Pritykin, Michail Schizas, Jacob Verter, Wei Hu, Zhong-Min Wang, Fanny Matheis, Daniel Mucida, Louis-Marie Charbonnier, Talal A. Chatila, Alexander Y. Rudensky (2022). Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells. Immunity.

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Stanislav Dikiy, Andrew G. Levine, Yuri Pritykin, Chirag Krishna, Ariella Glasner, Christina S. Leslie, Alexander Y. Rudensky (2022). Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation. bioRxiv.

PDF DOI bioRxiv

Henri Schmidt, Minsi Zhang, Haralambos Mourelatos, Francisco J. Sánchez-Rivera, Scott W. Lowe, Andrea Ventura, Christina S. Leslie, Yuri Pritykin (2022). Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2. bioRxiv.

PDF DOI bioRxiv

Yi Zhong, Sarah Walker, Yuri Pritykin, Christina Leslie, Alexander Rudensky, Joris van der Veeken (2021). Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families. Nature Immunology.

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Minggang Zhang, Zeguo Zhao, Yuri Pritykin, Margaret Hannum, Andrew C. Scott, Fengshen Kuo, Viraj Sanghvi, Timothy A. Chan, Venkatraman Seshan, Hans-Guido Wendel, Andrea Schietinger, Michel Sadelain, Morgan Huse (2021). Ectopic activation of the miR-200c–EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy. Science Translational Medicine.

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Yuri Pritykin, Joris van der Veeken, Allison Pine, Yi Zhong, Merve Sahin, Linas Mazutis, Dana Pe’er, Alexander Rudensky, Christina Leslie (2021). A unified atlas of CD8 T cell dysfunctional states in cancer and infection. Molecular Cell.

PDF DOI bioRxiv

Clarissa Campbell, Francois Marchildon, Anthony J. Michaels, Naofumi Takemoto, Joris van der Veeken, Michail Schizas, Yuri Pritykin, Christina S. Leslie, Andrew M. Intlekofer, Paul Cohen, Alexander Y. Rudensky (2020). FXR mediates T cell-intrinsic responses to reduced feeding during infection. Proceedings of the National Academy of Sciences.

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Xiaoyi Li, Yuri Pritykin, Carla P Concepcion, Yuheng Lu, Gaspare La Rocca, Minsi Zhang, Bryan King, Peter J Cook, Yu Wah Au, Olesja Popow, Joao A.Paulo, Hannah G Otis, Chiara Mastroleo, Paul Ogrodowski, Ryan Schreiner, Kevin M Haigis, Doron Betel, Christina S Leslie, Andrea Ventura (2020). High-Resolution in vivo identification of miRNA targets by Halo-enhanced Ago2 pull-down. Molecular Cell.

PDF DOI bioRxiv

Chrysothemis C Brown, Herman Gudjonson, Yuri Pritykin, Deeksha Deep, Vincent-Philippe Lavallée, Alejandra Mendoza, Rachel Fromme, Linas Mazutis, Charlotte Ariyan, Christina Leslie, Dana Pe’er, Alexander Y Rudensky (2019). Transcriptional basis of mouse and human dendritic cell heterogeneity. Cell.

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Catherine Konopacki, Yuri Pritykin, Yury Rubtsov, Christina S. Leslie, Alexander Y. Rudensky (2019). Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function. Nature Immunology.

PDF DOI rdcu

Colleen M Lau, Nicholas M Adams, Clair D Geary, Orr-El Weizman, Moritz Rapp, Yuri Pritykin, Christina S Leslie, Joseph C Sun (2018). Epigenetic control of innate and adaptive immune memory. Nature Immunology.

DOI rdcu

Clair D Geary, Chirag Krishna, Colleen M Lau, Nicholas M Adams, Sofia V Gearty, Yuri Pritykin, Allan R Thomsen, Christina S Leslie, Joseph C Sun (2018). Non-redundant ISGF3 components promote NK cell survival in an auto-regulatory manner during viral infection. Cell Reports.

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Orr-El Weizman, Nicholas M. Adams, Iona S. Schuster, Chirag Krishna, Yuri Pritykin, Colleen Lau, Mariapia A. Degli-Esposti, Christina S. Leslie, Joseph C. Sun, Timothy E. O'Sullivan (2017). ILC1 Confer Early Host Protection at Initial Sites of Viral Infection. Cell.

DOI PMC

Yuri Pritykin, Tarcisio Brito, Trudi Schupbach, Mona Singh, Attilio Pane (2017). Integrative analysis unveils new functions for the Drosophila Cutoff protein in non-coding RNA biogenesis and gene regulation. RNA.

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Alexendar R Perez, Yuri Pritykin, Joana A Vidigal, Sagar Chhangawala, Lee Zamparo, Christina S Leslie, Andrea Ventura (2017). GuideScan software for improved single and paired CRISPR guide RNA design. Nature Biotechnology.

PDF DOI rdcu PMC

Säida Dadi, Sagar Chhangawala, Benjamin M. Whitlock, Ruth A. Franklin, Chong T. Luo, Soyoung A. Oh, Ahmed Toure, Yuri Pritykin, Morgan Huse, Christina S. Leslie, Ming O. Li (2016). Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells. Cell.

DOI PMC

Yuri Pritykin, Dario Ghersi, Mona Singh (2015). Genome-Wide Detection and Analysis of Multifunctional Genes. PLOS Computational Biology.

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Yuri Pritykin (2014). Classifications of protein roles in the functional organization of the cell. PhD Thesis.

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Yuri Pritykin, Mona Singh (2013). Simple Topological Features Reflect Dynamics and Modularity in Protein Interaction Networks. PLOS Computational Biology.

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Maxim Zhukovskiy, Dmitry Vinogradov, Yuri Pritykin, Liudmila Ostroumova, Evgeniy Grechnikov, Gleb Gusev, Pavel Serdyukov, Andrei Raigorodskii (2012). Empirical validation of the Buckley--Osthus model for the web host graph: degree and edge distributions. Proceedings of the 21st ACM international conference on Information and knowledge management (CIKM'12).

DOI arXiv

Yuri Pritykin (2010). Almost periodicity, finite automata mappings, and related effectiveness issues. Russian Mathematics.

PDF DOI Russian arXiv

Francois Nicolas, Yuri Pritykin (2009). On uniformly recurrent morphic sequences. International Journal of Foundations of Computer Science.

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Юрий Притыкин (Yuri Pritykin) (2009). О логических теориях и конечных автоматах на бесконечных последовательностях. Фундаментальная математика в работах молодых ученых (Fundamental mathematics in the work of young researchers).

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Юрий Притыкин (Yuri Pritykin) (2009). Алгоритмические свойства последовательностей, близких к периодическим. Диссертация на соискание ученой степени кандидата физико-математических наук (Candidate of Physical and Mathematical Sciences Dissertation).

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Yuri Pritykin, Julya Ulyashkina (2009). Aperiodicity Measure for Infinite Sequences. Computer Science in Russia—Lecture Notes in Computer Science 5675.

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Andrei Muchnik, Yuri Pritykin, Alexei Semenov (2009). Sequences close to periodic. Russian Mathematical Surveys.

DOI Russian arXiv

Yuri Pritykin (2007). On almost periodicity criteria for morphic sequences in some particular cases. Developments in language theory—Lecture Notes in Computer Science 4588.

DOI arXiv

Yuri Pritykin (2007). Information in Infinite Words. Proceedings of 6th International Conference on Words (WORDS 2007).

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Yuri Pritykin (2006). Finite-automaton transformations of strictly almost-periodic sequences. Mathematical Notes.

PDF DOI Russian arXiv